E-ISSN 2146-8362
 

Case Report 


Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation

Kanthilatha Pai, Pratap Kumar, Akhila Vasudeva.

Abstract
Placental site trophoblastic tumour (PSTT) is the least common form of gestational trophoblastic neoplasia accounting for only 1-2% of trophoblastic tumors. Approximately 200 cases are reported in English literature. PSTT presenting as a cervical growth is even less common. Differentiation of PSTT from other types of GTN, non-neoplastic gestational trophoblastic disease and non-trophoblastic tumors is important clinically due to differences in their therapeutic approaches.Appreciation of the morphologic features and immunophenotype allows their accurate diagnosis.Although most of the cases of PSTT behave in a benign fashion,the clinical behavior of PSTT can sometimes be variable and several prognostic factors can help to predict the biological behavior of this condition. We report a rare case of placental site trophoblastic tumor, presenting as a cervical mass, in a 38 year old female, and review the literature.

Key words: Gestational trophoblastic disease, Placental site trophoblastic tumor, Cervical


 
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REFERENCES
Hassadia A, Gillespie A, Tidy J, Everard RGNJ, Wells M, Coleman R, Hancock B. Placental site trophoblastic tumour: clinical features and management. Gynecol Oncol 2005; 99:603–7.

http://dx.doi.org/10.1016/j.ygyno.2005.06.054

[Pubmed]   
Behtash N, Zarchi MK. Placental site trophoblastic tumor. J Cancer Res Clin Oncol 2008; 134:1–6.

http://dx.doi.org/10.1007/s00432-007-0208-y

[Pubmed]   
McLellan R, Buscema J, Currie JL, Woodruff JD. Placental site trophoblastic tumor in a postmenopausal woman. Am J Clin Pathol 1991; 95:670-5

[Pubmed]   

Rutgers JL, Baergen RN, Young RH, Scully RE. Placental site trophoblastic tumor: Clinicopathological study of 64 cases. Mod Pathol 1995;8:96 A

Zwischenberger BA, Boren T. Placental site trophoblastic tumor presenting as a friable cervical mass. Eur J Gynaecol Oncol 2010; 31(5): 570-2.

[Pubmed]   
Chang YL, Chang TC, Hsueh S, Huang KG, Wang PN, Liu HP, Soong YK. Prognostic factors and treatment of Placental site trophoblastic tumor: report of 3 cases and analysis of 88 cases. Gynaecol Oncol 1999; 73:216

http://dx.doi.org/10.1006/gyno.1999.5344

[Pubmed]   
Papadopoulos AJ, Foskett M, Seckl MJ, McNeish I, Paradinas FJ, Rees H, Newlands ES Twenty-five years' clinical experience with placental site trophoblastic tumors. J Reprod Med 2002; 47:460–4.

[Pubmed]   

How to Cite this Article
Pubmed Style

Pai K, Kumar P, Vasudeva A. Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation. J Interdiscip Histopathol. 2013; 1(5): 286-289. doi:10.5455/jihp.20130723051544


Web Style

Pai K, Kumar P, Vasudeva A. Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation. http://www.ejmjih.com/?mno=40463 [Access: October 15, 2018]. doi:10.5455/jihp.20130723051544


AMA (American Medical Association) Style

Pai K, Kumar P, Vasudeva A. Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation. J Interdiscip Histopathol. 2013; 1(5): 286-289. doi:10.5455/jihp.20130723051544



Vancouver/ICMJE Style

Pai K, Kumar P, Vasudeva A. Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation. J Interdiscip Histopathol. (2013), [cited October 15, 2018]; 1(5): 286-289. doi:10.5455/jihp.20130723051544



Harvard Style

Pai, K., Kumar, P. & Vasudeva, A. (2013) Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation. J Interdiscip Histopathol, 1 (5), 286-289. doi:10.5455/jihp.20130723051544



Turabian Style

Pai, Kanthilatha, Pratap Kumar, and Akhila Vasudeva. 2013. Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation. Journal of Interdisciplinary Histopathology, 1 (5), 286-289. doi:10.5455/jihp.20130723051544



Chicago Style

Pai, Kanthilatha, Pratap Kumar, and Akhila Vasudeva. "Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation." Journal of Interdisciplinary Histopathology 1 (2013), 286-289. doi:10.5455/jihp.20130723051544



MLA (The Modern Language Association) Style

Pai, Kanthilatha, Pratap Kumar, and Akhila Vasudeva. "Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation." Journal of Interdisciplinary Histopathology 1.5 (2013), 286-289. Print. doi:10.5455/jihp.20130723051544



APA (American Psychological Association) Style

Pai, K., Kumar, P. & Vasudeva, A. (2013) Primary Cervical Placental Site Trophoblastic Tumor: A Rare Entity with an Unusual Presentation. Journal of Interdisciplinary Histopathology, 1 (5), 286-289. doi:10.5455/jihp.20130723051544





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