E-ISSN 2146-8362
 

Original Research 


The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix

Ashwini Kolur, Ashok M Patil, Vaibhav Agarwal, Saeed Yendigiri, BB Sajjanar.

Abstract
Objectives: The mast cell remains an enigmatic cell, found resident in tissues throughout the body particularly in association with structures such as blood vessels and nerves. Various inflammatory disorders of the intestines, joints and lungs appear to be associated with an increase in mast cell numbers. The study was conducted on vermiform appendix. The present study was undertaken (1) to compare the mast cell and eosinophil counts in various layers of the appendix in various histopathological groups, and (2) to establish the relationship between the numbers of eosinophils and mast cells in the inflamed appendix.
Materials and Methods: The material for study consisted of appendix specimens received for histopathological examination in the Department of pathology. A 5 year study was conducted, 3 years retrospective and 2 years prospective.
Results: Out of 777 cases studied the incidence of appendicitis is high, in the first and second decades of life and slightly higher in females. Recurrent appendicitis was more common when compared to other inflamed appendices.
Conclusions: Eosinophil counts in all the layers were very high in acute eosinophilic appendicitis compared to normal appendices. A higher mast cell count was seen in acute eosinophilic appendicitis and recurrent appendicitis. No correlation was found between mast cell and eosinophilic density. Our observations support the allergic theory of appendicitis rather than the obstructive theory.

Key words: Mast cells, Appendix, Eosinophils


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Ashwini Kolur
Articles by Ashok M Patil
Articles by Vaibhav Agarwal
Articles by Saeed Yendigiri
Articles by BB Sajjanar
on Google
on Google Scholar
Article Statistics
 Viewed: 2455
Downloaded: 585
Cited: 0

REFERENCES
1. Yong LC. The mast cell: origin, morphology, distribution, and function. Exp Toxicol Pathol 1997; 49(6): 409-24. [DOI via Crossref]   
2. Seema V, VL Pattankar. Mast cell variation in some commonly encountered lesions of salivary glands. Research Journal of Pharmaceutical, Biological and Chemical Sciences 2011; 2(2): 19-27.
3. Robbins and Cotran. Pathological Basis of Disease. In: Disease of Immune System. 8th edition, Saunders Elsevier, Philadelphia, USA, pp 198-199, 2010
4. Williams GR. Presidential Address: a history of appendicitis. With anecdotes illustrating its importance. Ann Surg 1983; 197(5): 495-506. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
5. Aravindan KP, Vijayaraghavan D, Manipadam MT. Acute eosinophilic appendicitis and the significance of eosinophil - Edema lesion. Indian J Pathol Microbiol 2010; 53(2): 258-261. [DOI via Crossref]    [Pubmed]   
6. Crabbe MM, Norwood SH, Robertson HD, Silva JS. Recurrent and chronic appendicitis. Surg Gynecol Obstet 1986; 163(1): 11-13. [Pubmed]   
7. LEE JA. The influence of sex and age on appendicitis in children and young adults. Gut 1962; 3: 80-84. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
8. Althoubaity FK. Suspected acute appendicitis in female patients. Trends in diagnosis in emergency department in a University Hospital in Western region of Saudi Arabia. Saudi Med J 2006; 27(11): 1667-1673. [Pubmed]   
9. Singh UR, Malhotra A, Bhatia A. Eosinophils, mast cells, nerves and ganglion cells in appendicitis. Indian J Surg 2008; 70(5): 231-234. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
10. Mysorekar VV, Chanda S, Dandeka CP. Mast cells in surgically resected appendices. Indian J Pathol Microbiol 2006; 49(2): 229-233. [Pubmed]   
11. Maurer M, Theoharides T, Granstein RD, Bischoff SC, Bienenstock J, Henz B, Kovanen P, Piliponsky AM, Kambe N, Vliagoftis H, Levi-Schaffer F, Metz M, Miyachi Y, Befus D, Forsythe P, Kitamura Y, Galli S. What is the physiological function of mast cells? Exp Dermatol 2003; 12(6): 886-910. [DOI via Crossref]    [Pubmed]   

How to Cite this Article
Pubmed Style

Kolur A, Patil AM, Agarwal V, Yendigiri S, Sajjanar B. The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix. J Interdiscip Histopathol. 2014; 2(3): 150-153. doi:10.5455/jihp.20140512102819


Web Style

Kolur A, Patil AM, Agarwal V, Yendigiri S, Sajjanar B. The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix. http://www.ejmjih.com/?mno=151063 [Access: August 16, 2018]. doi:10.5455/jihp.20140512102819


AMA (American Medical Association) Style

Kolur A, Patil AM, Agarwal V, Yendigiri S, Sajjanar B. The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix. J Interdiscip Histopathol. 2014; 2(3): 150-153. doi:10.5455/jihp.20140512102819



Vancouver/ICMJE Style

Kolur A, Patil AM, Agarwal V, Yendigiri S, Sajjanar B. The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix. J Interdiscip Histopathol. (2014), [cited August 16, 2018]; 2(3): 150-153. doi:10.5455/jihp.20140512102819



Harvard Style

Kolur, A., Patil, A. M., Agarwal, V., Yendigiri, S. & Sajjanar, B. (2014) The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix. J Interdiscip Histopathol, 2 (3), 150-153. doi:10.5455/jihp.20140512102819



Turabian Style

Kolur, Ashwini, Ashok M Patil, Vaibhav Agarwal, Saeed Yendigiri, and BB Sajjanar. 2014. The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix. Journal of Interdisciplinary Histopathology, 2 (3), 150-153. doi:10.5455/jihp.20140512102819



Chicago Style

Kolur, Ashwini, Ashok M Patil, Vaibhav Agarwal, Saeed Yendigiri, and BB Sajjanar. "The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix." Journal of Interdisciplinary Histopathology 2 (2014), 150-153. doi:10.5455/jihp.20140512102819



MLA (The Modern Language Association) Style

Kolur, Ashwini, Ashok M Patil, Vaibhav Agarwal, Saeed Yendigiri, and BB Sajjanar. "The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix." Journal of Interdisciplinary Histopathology 2.3 (2014), 150-153. Print. doi:10.5455/jihp.20140512102819



APA (American Psychological Association) Style

Kolur, A., Patil, A. M., Agarwal, V., Yendigiri, S. & Sajjanar, B. (2014) The Significance of Mast Cells and Eosinophils Counts in Surgically Resected Appendix. Journal of Interdisciplinary Histopathology, 2 (3), 150-153. doi:10.5455/jihp.20140512102819





Most Viewed Articles
  • Prevalence of Anemia and Associated Risk Factors among Pregnant Women Attending Antenatal Care in Azezo Health Center Gondar Town, Northwest Ethiopia
    Meseret Alem, Bamlaku Enawgaw, Aschalew Gelaw, Tigist Kenaw, Mohamed Seid , Yadesa Olkeba
    J Interdiscip Histopathol. 2013; 1(3): 137-144
    » Abstract & References » doi: 10.5455/jihp.20130122042052

  • Cytomorphometric Analysis of Oral Premalignant and Malignant Lesions Using Feulgen Stain and Exfoliative Brush Cytology.
    Priya Shirish Joshi, Manasi Sandipak Kaijkar
    J Interdiscip Histopathol. 2013; 1(4): 204-211
    » Abstract & References » doi: 10.5455/jihp.20130214064844

  • Differences in the Angiogenesis of Benign and Malignant Surface Epithelial Ovarian Tumors Demonstrated by Microvessel Density and Immunohistochemistry
    Shelly Sehgal, Prashant Goyal, Reena Agarwal, Sompal Singh, Awanindra Kumar, Ruchika Gupta, Vinita Kumar, Dipti Agrawal
    J Interdiscip Histopathol. 2013; 1(3): 145-152
    » Abstract & References » doi: 10.5455/jihp.20130204114930

  • The Role of CD10 Immunohistochemistry in the Grading of Phyllodes Tumour of The Breast
    Huzlinda Hussin,Jayalakshmi Pailoor, Peh Suat Cheng
    J Interdiscip Histopathol. 2013; 1(4): 195-203
    » Abstract & References » doi: 10.5455/jihp.20130307011432

  • Retroperitoneal Non-functioning Paraganglioma: A Case Report
    Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya
    J Interdiscip Histopathol. 2013; 1(3): 168-171
    » Abstract & References » doi: 10.5455/jihp.20130115114630

  • P53 Immunohistochemical Staining Patterns in Benign, Premalignant and Malignant Lesions of the Oral Cavity: A Study of 68 Cases
    Pankaj Baweja, Vidya Monappa, Geetha Krishnanand
    J Interdiscip Histopathol. 2013; 1(3): 113-120
    » Abstract & References » doi: 10.5455/jihp.20130121120725

  • Nonspecific Cecal Ulcer: An Obsolete Jargon
    Duvuru Ram, Vilvapathy Senguttuvan Karthikeyan, Sarath Chandra Sistla
    J Interdiscip Histopathol. 2013; 1(2): 85-88
    » Abstract & References » doi: 10.5455/jihp.20121228043742

  • Histopathology as diagnostic tool for Ascosphaera apis infection in apparently healthy honey bees (Apis mellifera ligustica)
    Paola Maiolino, Francesca Carella, Giovanna De Leva, Laura Rinaldi, Giuseppe Cringoli, Manuela Martano
    J Interdiscip Histopathol. 2013; 1(3): 160-162
    » Abstract & References » doi: 10.5455/jihp.20130128010436

  • Double-Hit Lymphoma Presenting as Primary Renal Lymphoma: A Case Report
    Vikas Mehta, Chad Ellimottil, Jodi Speiser, Milind Velankar, Guliz A Barkan
    J Interdiscip Histopathol. 2013; 1(2): 93-97
    » Abstract & References » doi: 10.5455/jihp.20130121075815

  • Lateral Periodontal Cyst: A Report of Two Cases with Varying Clinico-Radiological Features
    Preethi Balan, Subhas G Babu, Shishir Shetty, Deepa Dsouza
    J Interdiscip Histopathol. 2012; 1(1): 41-44
    » Abstract & References » doi: 10.5455/jihp.20120808010902

  • Most Downloaded
  • Prevalence of Anemia and Associated Risk Factors among Pregnant Women Attending Antenatal Care in Azezo Health Center Gondar Town, Northwest Ethiopia
    Meseret Alem, Bamlaku Enawgaw, Aschalew Gelaw, Tigist Kenaw, Mohamed Seid , Yadesa Olkeba
    J Interdiscip Histopathol. 2013; 1(3): 137-144
    » Abstract & References » doi: 10.5455/jihp.20130122042052

  • Cytomorphometric Analysis of Oral Premalignant and Malignant Lesions Using Feulgen Stain and Exfoliative Brush Cytology.
    Priya Shirish Joshi, Manasi Sandipak Kaijkar
    J Interdiscip Histopathol. 2013; 1(4): 204-211
    » Abstract & References » doi: 10.5455/jihp.20130214064844

  • P53 Immunohistochemical Staining Patterns in Benign, Premalignant and Malignant Lesions of the Oral Cavity: A Study of 68 Cases
    Pankaj Baweja, Vidya Monappa, Geetha Krishnanand
    J Interdiscip Histopathol. 2013; 1(3): 113-120
    » Abstract & References » doi: 10.5455/jihp.20130121120725

  • Small Cell Lung Carcinoma: Better Than Its Reputation? A Population Based Study
    Hans Rostad, Erik Heyerdahl Strom, Helge Scott, Maria Ramnefjell, Kjell Kjellevold
    J Interdiscip Histopathol. 2012; 1(1): 1-4
    » Abstract & References » doi: 10.5455/jihp.20120703032839

  • Stented Vessels: A Challenge for Histological Preparation and Microscopy
    Andrea Nolte, Theresa Braun, Sven Zur Oven Krockhaus, Adelheid Munz, Ulrich Vogel, Christian Schlensak, Hans Wendel, Tobias Walker
    J Interdiscip Histopathol. 2013; 1(3): 104-112
    » Abstract & References » doi: 10.5455/jihp.20130306112937

  • Histopathology of the Liver Following Administration of Artesunate in Adult Wistar Rats
    Felix Monday Onyije, Josiah S Hart
    J Interdiscip Histopathol. 2012; 1(1): 26-29
    » Abstract & References » doi: 10.5455/jihp.20120606081137

  • Role of HPV Vaccine in the Prevention of Cervical Cancer
    Saleh JA, Yusuph H, Zailani ZB
    J Interdiscip Histopathol. 2013; 1(4): 212-216
    » Abstract & References » doi: 10.5455/jihp.20130119122700

  • Lateral Periodontal Cyst: A Report of Two Cases with Varying Clinico-Radiological Features
    Preethi Balan, Subhas G Babu, Shishir Shetty, Deepa Dsouza
    J Interdiscip Histopathol. 2012; 1(1): 41-44
    » Abstract & References » doi: 10.5455/jihp.20120808010902

  • Histopathological Effects of Varied Fluoride Concentration on Cerebrum in Albino Rats
    Sajad Hamid, Zaffar Kawoosa, Shahnawaz Hamid, M.A. Mir, Athar Hafiz, Irfan Jan, Fayiza Yaqoob
    J Interdiscip Histopathol. 2012; 1(1): 30-34
    » Abstract & References » doi: 10.5455/jihp.20121105123701

  • The Role of CD10 Immunohistochemistry in the Grading of Phyllodes Tumour of The Breast
    Huzlinda Hussin,Jayalakshmi Pailoor, Peh Suat Cheng
    J Interdiscip Histopathol. 2013; 1(4): 195-203
    » Abstract & References » doi: 10.5455/jihp.20130307011432

  • Most Cited Articles
  • Prevalence of Anemia and Associated Risk Factors among Pregnant Women Attending Antenatal Care in Azezo Health Center Gondar Town, Northwest Ethiopia
    Meseret Alem, Bamlaku Enawgaw, Aschalew Gelaw, Tigist Kenaw, Mohamed Seid , Yadesa Olkeba
    J Interdiscip Histopathol. 2013; 1(3): 137-144
    » Abstract & References » doi: 10.5455/jihp.20130122042052
    Cited : 19 times [Click to see citing articles]

  • Renal Biopsy for Research: An Overview of Russian Experience
    Sergei V. Jargin
    J Interdiscip Histopathol. 2014; 2(2): 88-95
    » Abstract & References » doi: 10.5455/jihp.20140312020838
    Cited : 4 times [Click to see citing articles]

  • Cadmium-Induced Testicular Toxicity, Oxidative Stress and Histopathology in Wistar Rats: Sustained Effects of Polyphenol-Rich Extract of Vernonia Amygdalina (Del.) Leaf
    Christian Eseigbe Imafidon, Olatoye Taiwo Risikat, Bamidele Funminiyi Samuel, Ojo Opeyemi Esther, Ademoye Kehinde Aderonke
    J Interdiscip Histopathol. 2016; 4(3): 54-62
    » Abstract & References » doi: 10.5455/jihp.20160618041629
    Cited : 4 times [Click to see citing articles]

  • Characterization of the Blood Brain Barrier in Pediatric Central Nervous System Neoplasms
    Christopher S Hong, Winson Ho, Martin G Piazza, Abhik Ray-Chaudhury, Zhengping Zhuang, John D Heiss
    J Interdiscip Histopathol. 2016; 4(2): 29-33
    » Abstract & References » doi: 10.5455/jihp.20160623053540
    Cited : 4 times [Click to see citing articles]

  • The Senescence Process of Internal Thoracic Artery
    Antonio Manenti, Luca Roncati, Giuseppe Barbolini, Francesco Rivasi
    J Interdiscip Histopathol. 2013; 1(2): 58-61
    » Abstract & References » doi: 10.5455/jihp.20121211115233
    Cited : 3 times [Click to see citing articles]

  • Primary Biliary Cirrhosis Overlapping with Autoimmune Hepatitis in an HIV-Infected Patient on Antiretroviral Therapy
    Margaret Rae Caplan, Apurva Trivedi, Mary McLaughlin, Annick Hebou, David Kleiner, Theo Heller, Caryn Morse
    J Interdiscip Histopathol. 2013; 1(5): 270-273
    » Abstract & References » doi: 10.5455/jihp.20130624104921
    Cited : 3 times [Click to see citing articles]

  • Evaluation of Amelotin Expression in Benign Odontogenic Tumors
    Daiana Paula Stolf, Tae-Young Lee, Grace Bradley, Bernhard Ganss
    J Interdiscip Histopathol. 2013; 1(5): 236-245
    » Abstract & References » doi: 10.5455/jihp.20130506045106
    Cited : 2 times [Click to see citing articles]

  • Diffuse Cutaneous Leishmaniasis in an HIV Sero-Positive Patient - A Diagnostic Dilemma
    Kumar U Mahesh, Balasaheb Ramling Yelikar, Ratnakar Madhav Rao Potekar, Palin Aparna, Murthy Keshav
    J Interdiscip Histopathol. 2012; 1(1): 45-47
    » Abstract & References » doi: 10.5455/jihp.20121109060828
    Cited : 2 times [Click to see citing articles]

  • Small Cell Lung Carcinoma: Better Than Its Reputation? A Population Based Study
    Hans Rostad, Erik Heyerdahl Strom, Helge Scott, Maria Ramnefjell, Kjell Kjellevold
    J Interdiscip Histopathol. 2012; 1(1): 1-4
    » Abstract & References » doi: 10.5455/jihp.20120703032839
    Cited : 2 times [Click to see citing articles]

  • Association of Claudin-1 with E-Cadherin/Catenin Complex, Microvessel Density (MVD)-Related Markers, and Clinicopathological Features in Colorectal Carcinoma
    Urania Skoufi, Dimitrios L Arvanitis, Litsa Lampri, Elli Ioachim, Jim Koutsogiannis, Christina Skoufi, Dimitris Tsironis and Antigony Mitselou
    J Interdiscip Histopathol. 2014; 2(3): 135-144
    » Abstract & References » doi: 10.5455/jihp.20140429121735
    Cited : 2 times [Click to see citing articles]